ESPRIT is a standard implementation of complete-linkage based hierarchical clustering method. It can conformably process several tens of thousands sequences using a desktop computer. They have used the algorithm to process 1.1M human gut sequences using a small computer cluster consisting of 100 nodes

ESPRIT is a standard implementation of complete-linkage based hierarchical clustering method. It can conformably process several tens of thousands sequences using a desktop computer. They have used the algorithm to process 1.1M human gut sequences using a small computer cluster consisting of 100 nodes