Spiral Genetics provides a novel aligner/variant caller, Anchored Assembly, which can detect large structural variations using short read NGS data with unmatched precision.
标签：Alignment, DNA-Seq, Exome and Whole genome variant detection, De novo Assembly,Genomic Assembly, Mapping,Quality Control, Read alignment, Reference assembly,Resequencing, SNP discovery,Sequence analysis, Whole Genome Resequencing
Subread is a general-purpose read aligner which can be used to map both genomic DNA-seq reads and RNA-seq reads. It uses a new mapping paradigm called "seed-and-vote" to achieve fast, accurate and scalable read mapping. It automatically determines if a read should be globally or locally...
UnoSeq is a Java library to analyze next generation sequencing data (e.g. data generated by Illumina's mRNAseq method) and especially perform expression profiling in organisms where no well-annotated reference genome exists.
标签：RNA-Seq Alignment, De novo transcriptome assembly
A_purva is a Contact Map Overlap maximization (CMO) solver. Given two protein structures represented by two contact maps, A_purva computes the amino-acid alignment which maximize the number of common contacts.
A_purva is a Contact Map Overlap maximization (CMO) solver. Given two protei...