Summary: We present DisVis, a Python package and command line tool to calculate the reduced accessible interaction space of distance-restrained binary protein complexes, allowing for direct visualization and quantification of the information content of the distance restraints. The approach is general and can also be used as a knowledge-based distance energy term in FFT-based docking directly during the sampling stage.

Availability and implementation: The source code with documentation is freely available from https://github.com/haddocking/disvis.

Contact: a.m.j.j.bonvin@uu.nl

Supplementary information: Available at Bioinformatics online.