Nature Reviews Microbiology 13, 398 (2015)

Parasite biology: Punching through vacuolar membranes

Naomi Attar.
Some apicomplexan parasites, including Toxoplasma gondii and Plasmodium falciparum, replicate within parasitophorous vacuoles (PVs) after invading the host cell. Amino acids and other metabolites that are essential for parasite growth are delivered to the PV by transport through its membrane, which is made