PNAS

Protein synthesis during cellular quiescence is inhibited by phosphorylation of a translational elongation factor [Microbiology]

S. F. F. Pereira, R. L. Gonzalez, J. Dworkin.
In nature, most organisms experience conditions that are suboptimal for growth. To survive, cells must fine-tune energy-demanding metabolic processes in response to nutrient availability. Here, we describe a novel mechanism by which protein synthesis in starved cells is down-regulated by phosphorylation of the universally conserved elongation factor Tu (EF-Tu). Phosphorylation...