Nature Protocols 10, 1050 (2015)
Genome-wide profiling of in vivo RNA structure at single-nucleotide resolution using structure-seq
Yiliang Ding, Chun Kit Kwok, Yin Tang, Philip C Bevilacqua, Sarah M Assmann.
Structure-seq applies chemically based RNA structure probing on a genome-wide scale, allowing the in vivo structures of thousands of distinct transcripts to be discerned, and the meta-properties of RNA structure–function relationships to be unveiled.