Nature

Atomic structure of the APC/C and its mechanism of protein ubiquitination

Leifu Chang, Ziguo Zhang, Jing Yang, Stephen H. McLaughlin, David Barford.
A cryo-electron microscopy determination of the atomic structures of anaphase-promoting complex (APC/C)–coactivator complexes with either Emi1 or a UbcH10–ubiquitin conjugate.