Nature Methods

High-performance probes for light and electron microscopy

Sarada Viswanathan, Megan E Williams, Erik B Bloss, Timothy J Stasevich, Colenso M Speer, Aljoscha Nern, Barret D Pfeiffer, Bryan M Hooks, Wei-Ping Li, Brian P English, Teresa Tian, Gilbert L Henry, John J Macklin, Ronak Patel, Charles R Gerfen, Xiaowei Zhuang, Yalin Wang, Gerald M Rubin, Loren L Looger.
'Spaghetti monster' fluorescent proteins combine the power of conventional fluorescent proteins with the benefits of commonly used epitopes. These probes are demonstrated to be extremely versatile in diverse imaging applications.