Nature Methods
CONSERTING: integrating copy-number analysis with structural-variation detection
Xiang Chen, Pankaj Gupta, Jianmin Wang, Joy Nakitandwe, Kathryn Roberts, James D Dalton, Matthew Parker, Samir Patel, Linda Holmfeldt, Debbie Payne, John Easton, Jing Ma, Michael Rusch, Gang Wu, Aman Patel, Suzanne J Baker, Michael A Dyer, Sheila Shurtleff, Stephen Espy, Stanley Pounds, James R Downing, David W Ellison, Charles G Mullighan, Jinghui Zhang.
CONSERTING detects somatic copy-number alterations from whole-genome sequence data with high accuracy and sensitivity and identifies breakpoints even in heterogeneous or impure tumors.