Nature Methods 12, 493 (2015)
Reproducibility: changing the policies and culture of cell line authentication
Leonard P Freedman, Mark C Gibson, Stephen P Ethier, Howard R Soule, Richard M Neve, Yvonne A Reid.
Quality control of cell lines used in biomedical research is essential to ensure reproducibility. Although cell line authentication has been widely recommended for many years, misidentification, including cross-contamination, remains a serious problem. We outline a multi-stakeholder, incremental approach and policy-related recommendations to facilitate change in the culture of cell line authentication.